Id say WWE No Mercy 2. I mean they tried to go other ways with wrestling games and have failed. Id love to see them go back to there roots with the no Mercy engine and just amp up the graphics, But thats just me.
Id also LOVE to see a sequal to Final Fantasy VII. I mean, i never played it but i watched a friend play it alot and from what I hear its hands down the best FF if not the best RPG of all time. Id much prefer a sequal to that then FF X. Final Fantasy Ten was good but didnt really wow me.
I do belive theres allready been a Tony Hawk 3. And theres a sequal to that on the way called Tony Hawk Under Ground (Or something to that effect) Thats supposed to be kick ass
Also...BLIZZARD, PLEASE MAKE A STAR CRAFT SEQUAL !!. Id love to have a great RTS to play over X Box Live. I know Star Craft Ghost is coming out eventually, and it looks friggin awesome, but im itchin for an RTS here.
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The kinder, gentler, Vicious 
Beretta55- "fo sheezy heezy neezy weezy flipity floppity floop"
Lost Myth- "I already know you are something special and I think the Pistons did too,
because then why would they have won the trophy on your birthday dude?
Anonymous- "Whos more to blame, me for being quote un quote gullible ?, or him for lying !?"